Optimization of collective enzyme activity via spatial localization

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Optimization of collective enzyme activity via spatial localization.

The spatial organization of enzymes often plays a crucial role in the functionality and efficiency of enzymatic pathways. To fully understand the design and operation of enzymatic pathways, it is therefore crucial to understand how the relative arrangement of enzymes affects pathway function. Here we investigate the effect of enzyme localization on the flux of a minimal two-enzyme pathway withi...

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ژورنال

عنوان ژورنال: The Journal of Chemical Physics

سال: 2013

ISSN: 0021-9606,1089-7690

DOI: 10.1063/1.4823504